Qwen 3.5 397B-A17B — GB200 NVL72 vs MI300X Performance per Dollar
Cost per million tokens of GB200 NVL72 (NVIDIA Blackwell) versus MI300X (AMD CDNA 3) on Qwen 3.5 397B-A17B. Large-hyperscaler-volume ownership TCO normalized by total tokens — performance per dollar across LLM workloads. Pick the more cost-efficient SKU at every target interactivity level. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
AgentX replays real coding-agent sessions rather than fixed-length prompts, so context grows turn over turn and most of each request is served from cache instead of being recomputed. That turns the comparison into a systems question: KV transfer between nodes, prefix-aware routing, and cache capacity all move the curve alongside raw chip throughput. Fixed-sequence workloads stay the clean baseline for kernel and silicon performance, so the two scenarios answer different questions about the same hardware. Learn more about AgentX →
Only GB200 NVL72 has cost data at 168 tok/s/user on Qwen 3.5 397B-A17B — $0.01 per million tokens. MI300X is unmeasured at this target.
GB200 NVL72 costs $0.02 per million tokens at 287 tok/s/user on Qwen 3.5 397B-A17B; we have no MI300X benchmark data at this exact target.
At 405 tok/s/user on Qwen 3.5 397B-A17B, GB200 NVL72 comes in at $0.06 per million tokens. MI300X hasn't been benchmarked at this operating point. (Numbers reflect the default agentic-traces · fp4 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
Chip pricing (owning hyperscaler): GB200 NVL72 $1.86/chip/hr · MI300X $0.95/chip/hr. Source: SemiAnalysis Market July 2026 Pricing Surveys & AI Cloud TCO Model.

| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Dollar per Million Tokens | GB200 NVL72:$0.010MI300X:— | GB200 NVL72:$0.021MI300X:— | GB200 NVL72:$0.056MI300X:— |
| Concurrency | GB200 NVL72:~23MI300X:— | GB200 NVL72:~15MI300X:— | GB200 NVL72:~6MI300X:— |