Head-to-head AI inference benchmark comparison of MI355X (AMD CDNA 4) and RTX PRO 6000 (NVIDIA Blackwell) on Qwen 3.5 397B-A17B. Latency, throughput, and cost across LLM workloads. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
AgentX replays real coding-agent sessions rather than fixed-length prompts, so context grows turn over turn and most of each request is served from cache instead of being recomputed. That turns the comparison into a systems question: KV transfer between nodes, prefix-aware routing, and cache capacity all move the curve alongside raw chip throughput. Fixed-sequence workloads stay the clean baseline for kernel and silicon performance, so the two scenarios answer different questions about the same hardware. Learn more about AgentX →
MI355X: 38865 tok/s/chip, $0.01 per million tokens at 101 tok/s/user on Qwen 3.5 397B-A17B. RTX PRO 6000 is unmeasured here.
At 172 tok/s/user on Qwen 3.5 397B-A17B, MI355X delivers 20776 tok/s/chip at $0.02 per million tokens; RTX PRO 6000 hasn't been benchmarked at this target.
MI355X hits 6192 tok/s/chip for $0.07 per million tokens at 243 tok/s/user on Qwen 3.5 397B-A17B. No RTX PRO 6000 data at this operating point. (Numbers reflect the default agentic-traces · fp8 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Throughput (tok/s/chip) | MI355X:38865.3RTX PRO 6000:— | MI355X:20776.2RTX PRO 6000:— | MI355X:6191.8RTX PRO 6000:— |
| Cost ($/M tok) | MI355X:$0.011RTX PRO 6000:— | MI355X:$0.020RTX PRO 6000:— | MI355X:$0.067RTX PRO 6000:— |
| tok/s/MW | MI355X:18595855RTX PRO 6000:— | MI355X:9940742RTX PRO 6000:— | MI355X:2962575RTX PRO 6000:— |
| Concurrency | MI355X:~33RTX PRO 6000:— | MI355X:~15RTX PRO 6000:— | MI355X:~4RTX PRO 6000:— |
Agentic inference metrics from the AgentX scenario and fixed-sequence inference metrics across models, hardware configurations, and serving parameters.
TCO $/chip/hr:
Source: SemiAnalysis Market July 2026 Pricing Surveys & AI Cloud TCO Model
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate cost per million tokens per decode chip or per prefill chip, rather than per total chip count. This makes direct token cost comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate input throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct input throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate output throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct output throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate power per decode chip or per prefill chip, rather than per total chip count. This makes direct power comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate Joules per decode chip or per prefill chip, rather than per total chip count. This makes direct Joules per token comparison with aggregated configs not an apples-to-apples comparison.
Matching measurements exist, but their chip series are hidden.
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1 The ATOM engine is promising, however it has yet to serve production tokens. It is still in its infant stage.
Qwen3.5 397B 8K / 1K Total Tokens per $1 TCO vs. Median Interactivity