Head-to-head AI inference benchmark comparison of H100 (NVIDIA Hopper) and MI300X (AMD CDNA 3) on MiniMax M3 428B. Latency, throughput, and cost across LLM workloads. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
AgentX replays real coding-agent sessions rather than fixed-length prompts, so context grows turn over turn and most of each request is served from cache instead of being recomputed. That turns the comparison into a systems question: KV transfer between nodes, prefix-aware routing, and cache capacity all move the curve alongside raw chip throughput. Fixed-sequence workloads stay the clean baseline for kernel and silicon performance, so the two scenarios answer different questions about the same hardware. Learn more about AgentX →
At 13 tok/s/user interactivity on MiniMax M3 428B, H100 delivers 654 tok/s/chip at $0.50 per million tokens; MI300X delivers 2644 tok/s/chip at $0.10. MI300X is 398% cheaper per token; MI300X delivers 305% more tok/s/chip at this point.
H100 posts 637 tok/s/chip for $0.51 per million tokens at 15 tok/s/user on MiniMax M3 428B; MI300X posts 2596 tok/s/chip for $0.10. MI300X is 402% cheaper per token; MI300X delivers 308% more tok/s/chip.
Throughput at 17 tok/s/user on MiniMax M3 428B: H100 hits 611 tok/s/chip, MI300X hits 2514. Per-million costs land at $0.53 and $0.10 respectively. MI300X is 407% cheaper per token; MI300X delivers 312% more tok/s/chip. (Numbers reflect the default agentic-traces · fp8 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Throughput (tok/s/chip) | H100:653.7MI300X:2644.3 | H100:637.0MI300X:2595.9 | H100:610.7MI300X:2513.7 |
| Cost ($/M tok) | H100:$0.497MI300X:$0.100 | H100:$0.510MI300X:$0.102 | H100:$0.532MI300X:$0.105 |
| tok/s/MW | H100:477121MI300X:1902375 | H100:464987MI300X:1867566 | H100:445754MI300X:1808407 |
| Concurrency | H100:~2MI300X:~10 | H100:~1MI300X:~9 | H100:~1MI300X:~8 |
Agentic inference metrics from the AgentX scenario and fixed-sequence inference metrics across models, hardware configurations, and serving parameters.
TCO $/chip/hr:
Source: SemiAnalysis Market July 2026 Pricing Surveys & AI Cloud TCO Model
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate cost per million tokens per decode chip or per prefill chip, rather than per total chip count. This makes direct token cost comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate input throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct input throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate output throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct output throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate power per decode chip or per prefill chip, rather than per total chip count. This makes direct power comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate Joules per decode chip or per prefill chip, rather than per total chip count. This makes direct Joules per token comparison with aggregated configs not an apples-to-apples comparison.
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MiniMax M3 428B 8K / 1K Total Tokens per $1 TCO vs. Interactivity