Head-to-head AI inference benchmark comparison of B300 (NVIDIA Blackwell) and MI355X (AMD CDNA 4) on GLM 5.3 744B. Latency, throughput, and cost across LLM workloads. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
AgentX replays real coding-agent sessions rather than fixed-length prompts, so context grows turn over turn and most of each request is served from cache instead of being recomputed. That turns the comparison into a systems question: KV transfer between nodes, prefix-aware routing, and cache capacity all move the curve alongside raw chip throughput. Fixed-sequence workloads stay the clean baseline for kernel and silicon performance, so the two scenarios answer different questions about the same hardware. Learn more about AgentX →
Near the low end of the 20–243 tok/s/user interactivity band, at 76 tok/s/user on GLM 5.3 744B: B300 runs 18415 tok/s/chip at $0.03/M tokens, MI355X runs 15679 at $0.03/M. MI355X is 28% cheaper per token; B300 delivers 17% more tok/s/chip.
Setting 132 tok/s/user as the target on GLM 5.3 744B, B300 produces 12258 tok/s/chip ($0.05 per million tokens) and MI355X produces 9291 ($0.04). MI355X is 14% cheaper per token; B300 delivers 32% more tok/s/chip.
At 188 tok/s/user interactivity on GLM 5.3 744B, B300 delivers 7086 tok/s/chip at $0.09 per million tokens; MI355X delivers 4479 tok/s/chip at $0.09. B300 is 5% cheaper per token; B300 delivers 58% more tok/s/chip at this point. (Numbers reflect the default agentic-traces · fp4 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Throughput (tok/s/chip) | B300:18414.8MI355X:15679.2 | B300:12257.6MI355X:9291.3 | B300:7086.1MI355X:4478.9 |
| Cost ($/M tok) | B300:$0.034MI355X:$0.027 | B300:$0.051MI355X:$0.045 | B300:$0.089MI355X:$0.093 |
| tok/s/MW | B300:9692023MI355X:7501992 | B300:6451370MI355X:4445575 | B300:3729544MI355X:2143013 |
| Concurrency | B300:~24MI355X:~10 | B300:~15MI355X:~5 | B300:~9MI355X:~2 |
Agentic inference metrics from the AgentX scenario and fixed-sequence inference metrics across models, hardware configurations, and serving parameters.
TCO $/chip/hr:
Source: SemiAnalysis Market July 2026 Pricing Surveys & AI Cloud TCO Model
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate cost per million tokens per decode chip or per prefill chip, rather than per total chip count. This makes direct token cost comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate input throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct input throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate output throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct output throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate power per decode chip or per prefill chip, rather than per total chip count. This makes direct power comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate Joules per decode chip or per prefill chip, rather than per total chip count. This makes direct Joules per token comparison with aggregated configs not an apples-to-apples comparison.
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GLM5.2/GLM5.3 744B 8K / 1K Total Tokens per $1 TCO vs. Interactivity