Qwen 3.5 397B-A17B — H100 vs MI300X Performance per Dollar
Cost per million tokens of H100 (NVIDIA Hopper) versus MI300X (AMD CDNA 3) on Qwen 3.5 397B-A17B. Owning-hyperscaler TCO normalized by output tokens — performance per dollar across LLM workloads. Pick the more cost-efficient SKU at every target interactivity level. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
Push Qwen 3.5 397B-A17B to 43 tok/s/user and H100 lands at $0.38 per million tokens against MI300X's $0.89 — H100 pulls ahead by 138%.
H100: $0.51 per million tokens. MI300X: $1.63. Both at 53 tok/s/user on Qwen 3.5 397B-A17B, with H100 223% cheaper.
Toward the upper edge of the 34–71 tok/s/user interactivity band — at 62 tok/s/user — H100 runs $0.69 per million tokens on Qwen 3.5 397B-A17B while MI300X runs $2.52. H100 is the cheaper choice by 265%. (Numbers reflect the default 1k/1k · fp8 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
GPU pricing (owning hyperscaler): H100 $1.30/GPU/hr · MI300X $1.12/GPU/hr. Source: SemiAnalysis Market August 2025 Pricing Surveys & AI Cloud TCO Model.

| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Dollar per Million Tokens | H100:$0.375MI300X:$0.893 | H100:$0.506MI300X:$1.633 | H100:$0.690MI300X:$2.517 |
| Concurrency | H100:~101MI300X:~34 | H100:~61MI300X:~15 | H100:~42MI300X:~8 |
Inference Performance
Inference performance metrics across different models, hardware configurations, and serving parameters.