Qwen 3.5 397B-A17B — MI325X vs MI355X Performance per Dollar
Cost per million tokens of MI325X (AMD CDNA 3) versus MI355X (AMD CDNA 4) on Qwen 3.5 397B-A17B. Owning-hyperscaler TCO normalized by output tokens — performance per dollar across LLM workloads. Pick the more cost-efficient SKU at every target interactivity level. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
MI325X: $0.76 per million tokens. MI355X: $0.15. Both at 46 tok/s/user on Qwen 3.5 397B-A17B, with MI355X 390% cheaper.
Around the middle of the 37–72 tok/s/user interactivity band — at 55 tok/s/user — MI325X runs $1.39 per million tokens on Qwen 3.5 397B-A17B while MI355X runs $0.17. MI355X is the cheaper choice by 700%.
On Qwen 3.5 397B-A17B at 64 tok/s/user, the per-million math comes out to $2.28 for MI325X and $0.20 for MI355X; MI355X delivers 1064% more output per dollar. (Numbers reflect the default 1k/1k · fp8 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
Chip pricing (owning hyperscaler): MI325X $1.10/chip/hr · MI355X $1.50/chip/hr. Source: SemiAnalysis Market July 2026 Pricing Surveys & AI Cloud TCO Model.
| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Dollar per Million Tokens | MI325X:$0.758MI355X:$0.155 | MI325X:$1.393MI355X:$0.174 | MI325X:$2.276MI355X:$0.195 |
| Concurrency | MI325X:~37MI355X:~116 | MI325X:~16MI355X:~85 | MI325X:~9MI355X:~68 |
Inference Performance
Agentic inference metrics from the AgentX scenario and fixed-sequence inference metrics across models, hardware configurations, and serving parameters.
Cost per Million Total Tokens (Owning - Hyperscaler) vs. Interactivity
Qwen3.5 397B • FP4 • 8K / 1K • Source: SemiAnalysis InferenceX™
TCO $/chip/hr: H100: 1.17H200: 1.22B200: 1.73B300: 2.26GB200: 1.86GB300: 2.31MI300X: 0.95MI325X: 1.1MI355X: 1.5RTX6000PRO: 0.68
Source: SemiAnalysis Market July 2026 Pricing Surveys & AI Cloud TCO Model
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate cost per million tokens per decode chip or per prefill chip, rather than per total chip count. This makes direct token cost comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate input throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct input throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate output throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct output throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate power per decode chip or per prefill chip, rather than per total chip count. This makes direct power comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate Joules per decode chip or per prefill chip, rather than per total chip count. This makes direct Joules per token comparison with aggregated configs not an apples-to-apples comparison.
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