Qwen 3.5 397B-A17B — GB300 NVL72 vs MI300X Performance per Dollar
Cost per million tokens of GB300 NVL72 (NVIDIA Blackwell) versus MI300X (AMD CDNA 3) on Qwen 3.5 397B-A17B. Owning-hyperscaler TCO normalized by output tokens — performance per dollar across LLM workloads. Pick the more cost-efficient SKU at every target interactivity level. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
Only GB300 NVL72 has cost data at 90 tok/s/user on Qwen 3.5 397B-A17B — $0.12 per million tokens. MI300X is unmeasured at this target.
GB300 NVL72 costs $0.26 per million tokens at 136 tok/s/user on Qwen 3.5 397B-A17B; we have no MI300X benchmark data at this exact target.
At 183 tok/s/user on Qwen 3.5 397B-A17B, GB300 NVL72 comes in at $0.55 per million tokens. MI300X hasn't been benchmarked at this operating point. (Numbers reflect the default 8k/1k · fp4 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
GPU pricing (owning hyperscaler): GB300 NVL72 $2.65/GPU/hr · MI300X $1.12/GPU/hr. Source: SemiAnalysis Market August 2025 Pricing Surveys & AI Cloud TCO Model.

| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Dollar per Million Tokens | GB300 NVL72:$0.122MI300X:— | GB300 NVL72:$0.256MI300X:— | GB300 NVL72:$0.553MI300X:— |
| Concurrency | GB300 NVL72:~71MI300X:— | GB300 NVL72:~21MI300X:— | GB300 NVL72:~7MI300X:— |
Inference Performance
Inference performance metrics across different models, hardware configurations, and serving parameters.